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  • Are bacteria able to get us to run faster?

    A recent research of the Harvard Medical School have been published on Nature Medicine by Scheiman et al., and showed the importance of human gut microbiome in athletes performance.






    The age of modern science is being increasingly characterized by the ability of researchers to have access to data and, within a broader context, by the creation of a sense of shared knowledge. Shared resources, such as data banks and literature, today represent the basis of the concept of the research work as much as experimental accuracy and substantial theoretical foundation...






  • BIL gate: A step toward a biological computer

    Scientists at Stanford University presented the remarkable production of genetic devices that work like a biological computer.

    The results, published on "Science" (28 March 2013), present the development of innovative genetic transistors that can be induced into biological cells and switched on/off in certain circumstances.


  • Web Server Issue of Nucleic Acids Research presents new free Array Analysis tools

    Nucleic Acids Research devotes a single issue in July to papers describing web-based software resources of value to the biological community.

    The emphasis of the current issue is on network and pathway analysis, high-throughput sequencing data analysis and biological text mining.



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Are bacteria able to get us to run faster?

   human microbiome

The pivotal role of the human gut microbiome in human health have been hugely demonstrated but Scheiman J. et al. published a recent study that opens new frontiers. 

The article published on Nature Medicine has the very eloquent title "Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism" and leads us to see gut microbiome under a new point of view. As demonstrated by Harvard Medical School researchers, not only gut bacteria are able to perform a pletora of tasks and actions having repercussions on human health and biochemical homeostasis, being thus linked to many states of human health and disease, but microbiome seems to be also able to alterate sports performance in humans. Jonathan Scheiman and collegues highlighted a strong link between members of the genus Veillonella and exercise performance studing microbioma of marathon runners. Scientists said "Veillonella utilize lactate as their sole carbon source, which prompted us to perform a shotgun metagenomic analysis in a cohort of elite athletes, finding that every gene in a major pathway metabolizing lactate to propionate is at higher relative abundance postexercise". They paved the idea that Veillonella atypica could be able to boost sports performance and decided to test this hypothesis by the inoculation of this bactieria into mice. Inoculated mice showed incredibly, an increase of the exhaustive treadmill run time, validating thus the finding that this strain of bacteria could alter the mechanisms behind muscle fatigue.

Is this the starting point for a targeted diet supplemention in athletes?

We will see surely in the future.

PhD, A. Fonzino

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By Adriano Fonzino, AllBioinformatics editorial staff on 01/07/2019

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